It’s no surprise that boo ’s popularity rose in the mid-19th century. This was the age of spiritualism, a widespread cultural obsession with paranormal phenomena that sent scores of people flocking to mediums and clairvoyants in hopes of communicating with the dead. Serious scientists were sending electrical shocks through the bodies of corpses to see if reanimating the dead was possible; readers were engrossed in terrifying Gothic fiction (think Frankenstein , Zastrozzi , and The Vampyre ); British police departments were reporting a heightened number of ghost sightings as graveyards were plagued by “ghost impersonators,” hoaxsters who camped out in cemeteries covered in white robes and pale chalk. It’s probably no coincidence that ghosts began to develop their own vocabulary—limited as it may be—during a period when everybody was curious about the goings-on within the spirit realm.
We wear the mask that grins and lies,
It hides our cheeks and shades our eyes,--
This debt we pay to human guile;
With torn and bleeding hearts we smile,
And mouth with myriad subtleties.
Why should the world be overwise,
In counting all our tears and sighs?
Nay, let them only see us, while
We wear the mask.
We smile, but, O great Christ, our cries
To thee from tortured souls arise.
We sing, but oh the clay is vile
Beneath our feet, and long the mile;
But let the world dream otherwise,
We wear the mask!
It is believed that palindromes frequently are also found in proteins,   but their role in the protein function is not clearly known. It has recently  been suggested that the prevalence existence of palindromes in peptides might be related to the prevalence of low-complexity regions in proteins, as palindromes frequently are associated with low-complexity sequences. Their prevalence might also be related to an alpha helical formation propensity of these sequences,  or in formation of proteins/protein complexes.